4OL9
Crystal Structure of putative 2-dehydropantoate 2-reductase PanE from Mycobacterium tuberculosis complexed with NADP and oxamate
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Putative 2-dehydropantoate 2-reductase | polymer | 304 | 32213.0 | 1 | UniProt (Q50648) Pfam (PF02558) Pfam (PF08546) UniProt (by SIFTS) (P9WIL1) | Mycobacterium tuberculosis | Ketopantoate reductase, KPA reductase, KPR |
| 2 | B (A) | NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | non-polymer | 743.4 | 1 | Chemie (NAP) PubChem (5885) PubChem (46936685) PubChem (4412) PubChem (90473931) PubChem (91972139) PubChem (145946263) PubChem (153311489) PubChem (174001641) PubChem (71717786) PubChem (165382010) | |||
| 3 | C (A) | OXAMIC ACID | non-polymer | 89.0 | 1 | Chemie (OXM) PubChem (974) | |||
| 4 | D (A) | ACETATE ION | non-polymer | 59.0 | 1 | Chemie (ACT) PubChem (175) | |||
| 5 | E (A) | CHLORIDE ION | non-polymer | 35.5 | 1 | Chemie (CL) PubChem (312) | |||
| 6 | F (A) | GLYCEROL | non-polymer | 92.1 | 1 | Chemie (GOL) PubChem (753) | |||
| 7 | G (A) | water | water | 18.0 | 283 | Chemie (HOH) |
Sequence modifications
A: 2 - 295 (UniProt: Q50648)
| PDB | External Database | Details |
|---|---|---|
| Met -8 | - | expression tag |
| Ala -7 | - | expression tag |
| His -6 | - | expression tag |
| His -5 | - | expression tag |
| His -4 | - | expression tag |
| His -3 | - | expression tag |
| His -2 | - | expression tag |
| His -1 | - | expression tag |
| Met 0 | - | expression tag |
| Ile 1 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 32213.0 | |
| Non-Polymers* | Number of molecules | 5 |
| Total formula weight | 1019.0 | |
| All* | Total formula weight | 33232.0 |
