4OKH
Crystal structure of calpain-3 penta-EF-hand domain
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C (A, B, C) | Calpain-3 | polymer | 189 | 22215.1 | 3 | UniProt (P20807) Pfam (PF21875) | Homo sapiens (human) | Calcium-activated neutral proteinase 3, CANP 3, Calpain L3, Calpain p94, Muscle-specific calcium-activated neutral protease 3, New calpain 1, nCL-1 |
| 2 | D, E, F, G, I... (A, B, C) | CALCIUM ION | non-polymer | 40.1 | 11 | Chemie (CA) | |||
| 3 | H, M (A, B) | 2,5,8,11,14,17,20,23,26,29,32,35,38,41,44,47,50,53,56,59,62,65,68,71,74,77,80-HEPTACOSAOXADOOCTACONTAN-82-OL | non-polymer | 1221.5 | 2 | Chemie (PEU) | |||
| 4 | Q, R, S (A, B, C) | water | water | 18.0 | 46 | Chemie (HOH) |
Sequence modifications
A, B, C: 642 - 821 (UniProt: P20807)
| PDB | External Database | Details |
|---|---|---|
| Met 641 | - | initiating methionine |
| Leu 822 | - | expression tag |
| Glu 823 | - | expression tag |
| His 824 | - | expression tag |
| His 825 | - | expression tag |
| His 826 | - | expression tag |
| His 827 | - | expression tag |
| His 828 | - | expression tag |
| His 829 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 66645.4 | |
| Non-Polymers* | Number of molecules | 13 |
| Total formula weight | 2883.8 | |
| All* | Total formula weight | 69529.2 |
