Loading
PDBj
MenuPDBj@FacebookPDBj@X(formerly Twitter)PDBj@BlueSkyPDBj@YouTubewwPDB FoundationwwPDBDonate
RCSB PDBPDBeBMRBAdv. SearchSearch help

4OI8

RAGE is a nucleic acid receptor that promotes inflammatory responses to DNA.

Replaces:  3S59
Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B
(A, B)
Advanced glycosylation end product-specific receptorpolymer22324195.62UniProt (Q15109)
Pfam (PF08205)
Homo sapiens (human)RAGE, Receptor for advanced glycosylation end products
2C
(E)
5'-D(*CP*CP*AP*TP*GP*AP*CP*TP*GP*TP*AP*GP*GP*AP*AP*AP*CP*TP*CP*TP*AP*GP*A)-3'polymer237073.61
3D
(F)
5'-D(*CP*TP*CP*TP*AP*GP*AP*GP*TP*TP*TP*CP*CP*TP*AP*CP*AP*GP*TP*CP*AP*TP*G)-3'polymer237006.51
4E, F
(A, B)
waterwater18.025Chemie (HOH)
Sequence modifications
A, B: 23 - 237 (UniProt: Q15109)
PDBExternal DatabaseDetails
Gly 19-expression tag
Ser 20-expression tag
Val 21-expression tag
Asp 22-expression tag
Ala 238-expression tag
Ala 239-expression tag
Ala 240-expression tag
Ser 241-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains4
Total formula weight62471.3
All*Total formula weight62471.3
*Water molecules are not included.

239492

PDB entries from 2025-07-30

PDB statisticsPDBj update infoContact PDBjnumon