4OI8

RAGE is a nucleic acid receptor that promotes inflammatory responses to DNA.

Replaces:  3S59

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B	Advanced glycosylation end product-specific receptor	polymer	223	24195.6	2	UniProt (Q15109) Pfam (PF08205) In PDB	Homo sapiens (human)	RAGE, Receptor for advanced glycosylation end products
2	E	5'-D(*CP*CP*AP*TP*GP*AP*CP*TP*GP*TP*AP*GP*GP*AP*AP*AP*CP*TP*CP*TP*AP*GP*A)-3'	polymer	23	7073.6	1
3	F	5'-D(*CP*TP*CP*TP*AP*GP*AP*GP*TP*TP*TP*CP*CP*TP*AP*CP*AP*GP*TP*CP*AP*TP*G)-3'	polymer	23	7006.5	1
4		water	water		18.0	25	Chemie (HOH)

Sequence modifications

A, B: 23 - 237 (UniProt: Q15109)

PDB	External Database	Details
Gly 19	-	expression tag
Ser 20	-	expression tag
Val 21	-	expression tag
Asp 22	-	expression tag
Ala 238	-	expression tag
Ala 239	-	expression tag
Ala 240	-	expression tag
Ser 241	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	62471.3
All*	Total formula weight	62471.3

*Water molecules are not included.