4OE4

Crystal Structure of Yeast ALDH4A1 Complexed with NAD+

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B	Delta-1-pyrroline-5-carboxylate dehydrogenase, mitochondrial	polymer	580	65111.3	2	UniProt (P07275) Pfam (PF00171) In PDB	Saccharomyces cerevisiae (Baker's yeast)	P5C dehydrogenase, L-glutamate gamma-semialdehyde dehydrogenase
2	A, B	NICOTINAMIDE-ADENINE-DINUCLEOTIDE	non-polymer		663.4	2	Chemie (NAD)
3		water	water		18.0	173	Chemie (HOH)

Sequence modifications

A, B: 23 - 575 (UniProt: P07275)

PDB	External Database	Details
Met 2	-	expression tag
Asp 3	-	expression tag
His 4	-	expression tag
His 5	-	expression tag
His 6	-	expression tag
His 7	-	expression tag
His 8	-	expression tag
His 9	-	expression tag
His 10	-	expression tag
His 11	-	expression tag
Ala 12	-	expression tag
Ser 13	-	expression tag
Glu 14	-	expression tag
Asn 15	-	expression tag
Leu 16	-	expression tag
Tyr 17	-	expression tag
Phe 18	-	expression tag
Gln 19	-	expression tag
Gly 20	-	expression tag
His 21	-	expression tag
Met 22	-	expression tag
Glu 576	-	expression tag
Leu 577	-	expression tag
Gly 578	-	expression tag
Ser 579	-	expression tag
Gly 580	-	expression tag
Cys 581	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	130222.5
Non-Polymers*	Number of molecules	2
	Total formula weight	1326.8
All*	Total formula weight	131549.4

*Water molecules are not included.