4ODG
Crystal structure of Staphylococcal nuclease variant V23I/V66I/V74I/V99I at cryogenic temperature
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Thermonuclease | polymer | 149 | 16899.4 | 1 | UniProt (P00644) Pfam (PF00565) | Staphylococcus aureus | TNase, Micrococcal nuclease, Staphylococcal nuclease |
| 2 | B (A) | THYMIDINE-3',5'-DIPHOSPHATE | non-polymer | 402.2 | 1 | Chemie (THP) | |||
| 3 | C (A) | CALCIUM ION | non-polymer | 40.1 | 1 | Chemie (CA) | |||
| 4 | D (A) | PHOSPHATE ION | non-polymer | 95.0 | 1 | Chemie (PO4) | |||
| 5 | E (A) | water | water | 18.0 | 61 | Chemie (HOH) |
Sequence modifications
A: 1 - 149 (UniProt: P00644)
| PDB | External Database | Details |
|---|---|---|
| Ile 23 | Val 105 | engineered mutation |
| Ile 66 | Val 148 | engineered mutation |
| Ile 74 | Val 156 | engineered mutation |
| Ile 99 | Val 181 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 16899.4 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 537.2 | |
| All* | Total formula weight | 17436.7 |
