4OAU
Complete human RNase L in complex with biological activators.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | C | 2-5A-dependent ribonuclease | polymer | 699 | 79416.3 | 1 | UniProt (Q05823) Pfam (PF00023) Pfam (PF00069) Pfam (PF06479) In PDB | Homo sapiens (human) | 2-5A-dependent RNase, Ribonuclease 4, Ribonuclease L, RNase L |
| 2 | A | RNA (5'-R(P*A*AP*A)-2') | polymer | 3 | 942.7 | 1 | |||
| 3 | C | ADENOSINE-5'-DIPHOSPHATE | non-polymer | 427.2 | 1 | Chemie (ADP) | |||
| 4 | C | MAGNESIUM ION | non-polymer | 24.3 | 2 | Chemie (MG) | |||
| 5 | water | water | 18.0 | 139 | Chemie (HOH) |
Sequence modifications
C: 21 - 719 (UniProt: Q05823)
| PDB | External Database | Details |
|---|---|---|
| Asn 672 | His 672 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 80359.0 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 475.8 | |
| All* | Total formula weight | 80834.8 |
