4OA5
X-ray crystal structure of an O-methyltransferase from Anaplasma phagocytophilum bound to SAH solved by iodide SAD phasing
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D, E... (A, B, C, D, E...) | O-methyltransferase family protein | polymer | 227 | 25309.2 | 6 | UniProt (Q2GKC7) | Anaplasma phagocytophilum | |
| 2 | CA, G, HD, NC, PB... (B, A, F, E, D...) | S-ADENOSYL-L-HOMOCYSTEINE | non-polymer | 384.4 | 6 | Chemie (SAH) PubChem (16760024) PubChem (193) PubChem (13792) PubChem (177678424) PubChem (189149) PubChem (439155) PubChem (25210495) PubChem (21125603) PubChem (44361184) PubChem (25203782) PubChem (46936206) PubChem (50989525) PubChem (51380914) PubChem (52224398) PubChem (57544532) PubChem (52224400) PubChem (59046843) PubChem (59170628) PubChem (59576228) PubChem (66805708) PubChem (5284331) PubChem (70689219) PubChem (70702054) PubChem (70832431) PubChem (71170554) PubChem (13231890) PubChem (6419189) PubChem (118374891) PubChem (118560068) PubChem (126969526) PubChem (129105892) PubChem (164157219) PubChem (143518505) PubChem (154578335) PubChem (163054214) PubChem (163335525) | |||
| 3 | AB, AC, AD, AE, BB... (C, D, E, F, B...) | IODIDE ION | non-polymer | 126.9 | 114 | Chemie (IOD) PubChem (30165) | |||
| 4 | AA, BA, ED, EE, FD... (A, E, F, B) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 10 | Chemie (EDO) | |||
| 5 | GD, JE, LC, MC (E, F, D) | GLYCEROL | non-polymer | 92.1 | 4 | Chemie (GOL) PubChem (753) | |||
| 6 | KE, LE, ME, NE, OE... (A, B, C, D, E...) | water | water | 18.0 | 849 | Chemie (HOH) |
Sequence modifications
A, B, C, D, E, F: 2 - 218 (UniProt: Q2GKC7)
| PDB | External Database | Details |
|---|---|---|
| Met -8 | - | expression tag |
| Ala -7 | - | expression tag |
| His -6 | - | expression tag |
| His -5 | - | expression tag |
| His -4 | - | expression tag |
| His -3 | - | expression tag |
| His -2 | - | expression tag |
| His -1 | - | expression tag |
| Met 0 | - | expression tag |
| Val 1 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 6 |
| Total formula weight | 151855.4 | |
| Non-Polymers* | Number of molecules | 134 |
| Total formula weight | 17762.6 | |
| All* | Total formula weight | 169618.0 |
