4O9U

Mechanism of transhydrogenase coupling proton translocation and hydride transfer

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, C (A, C)	NAD(P) transhydrogenase subunit alpha 2	polymer	100	10649.6	2	UniProt (Q72GR9)	Thermus thermophilus
2	B, D (B, D)	NAD(P) transhydrogenase subunit beta	polymer	450	47371.9	2	UniProt (Q72GS0)	Thermus thermophilus	Nicotinamide nucleotide transhydrogenase subunit beta
3	E, F (E, F)	NAD/NADP transhydrogenase alpha subunit 1	polymer	384	41258.8	2	UniProt (Q72GR8)	Thermus thermophilus
4	G, H (B, D)	NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE	non-polymer		743.4	2	Chemie (NAP) PubChem (5885) PubChem (46936685) PubChem (4412) PubChem (90473931) PubChem (91972139) PubChem (145946263) PubChem (153311489) PubChem (174001641) PubChem (71717786) PubChem (165382010)		Nicotinamide nucleotide transhydrogenase subunit beta
5	I, J (E, F)	NICOTINAMIDE-ADENINE-DINUCLEOTIDE	non-polymer		663.4	2	Chemie (NAD)

Sequence modifications

E, F: 1 - 375 (UniProt: Q72GR8)

PDB	External Database	Details
Met -8	-	expression tag
His -7	-	expression tag
His -6	-	expression tag
His -5	-	expression tag
His -4	-	expression tag
His -3	-	expression tag
His -2	-	expression tag
His -1	-	expression tag
His 0	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	6
	Total formula weight	198560.6
Non-Polymers*	Number of molecules	4
	Total formula weight	2813.7
All*	Total formula weight	201374.3

*Water molecules are not included.