4O67
Human cyclic GMP-AMP synthase (cGAS) in complex with GAMP
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Cyclic GMP-AMP synthase | polymer | 363 | 42536.1 | 2 | UniProt (Q8N884) Pfam (PF03281) Pfam (PF20266) | Homo sapiens | |
| 2 | C, E (A, B) | cGAMP | non-polymer | 674.4 | 2 | Chemie (1SY) | |||
| 3 | D, F (A, B) | ZINC ION | non-polymer | 65.4 | 2 | Chemie (ZN) | |||
| 4 | G, H (A, B) | water | water | 18.0 | 89 | Chemie (HOH) |
Sequence modifications
A, B: 161 - 522 (UniProt: Q8N884)
| PDB | External Database | Details |
|---|---|---|
| Met 160 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 85072.2 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 1479.6 | |
| All* | Total formula weight | 86551.8 |
