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4O61

Structure of human ALKBH5 crystallized in the presence of citrate

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B
(A, B)
RNA demethylase ALKBH5polymer22225339.02UniProt (Q6P6C2)
Pfam (PF13532)
Homo sapiens (human)Alkylated DNA repair protein alkB homolog 5, Alpha-ketoglutarate-dependent dioxygenase alkB homolog 5
2C, U
(A, B)
GLYCEROLnon-polymer92.12Chemie (GOL)
3D, V
(A, B)
CITRIC ACIDnon-polymer192.12Chemie (CIT)
4E, W
(A, B)
UNKNOWN LIGANDnon-polymer2Chemie (UNL)
5AA, BA, CA, DA, EA...
(B, A)
UNKNOWN ATOM OR IONnon-polymer30Chemie (UNX)
6MA, NA
(A, B)
waterwater18.0272Chemie (HOH)
Sequence modifications
A, B: 74 - 294 (UniProt: Q6P6C2)
PDBExternal DatabaseDetails
Gly 73-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight50678.0
Non-Polymers*Number of molecules36
Total formula weight568.4
All*Total formula weight51246.5
*Water molecules are not included.

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PDB entries from 2025-12-24

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