4O2W

Crystal structure of the third RCC1-like domain of HERC1

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D	E3 ubiquitin-protein ligase HERC1	polymer	404	42925.8	4	UniProt (Q15751) Pfam (PF00415) In PDB	Homo sapiens (human)	HECT domain and RCC1-like domain-containing protein 1, p532, p619
2	D, A, B	MAGNESIUM ION	non-polymer		24.3	3	Chemie (MG)
3	D, A	CHLORIDE ION	non-polymer		35.5	5	Chemie (CL)
4	D, A, B, C	UNKNOWN ATOM OR ION	non-polymer			25	Chemie (UNX)
5		water	water		18.0	673	Chemie (HOH)

Sequence modifications

A, B, C, D: 3975 - 4360 (UniProt: Q15751)

PDB	External Database	Details
Met 3957	-	expression tag
His 3958	-	expression tag
His 3959	-	expression tag
His 3960	-	expression tag
His 3961	-	expression tag
His 3962	-	expression tag
His 3963	-	expression tag
Ser 3964	-	expression tag
Ser 3965	-	expression tag
Gly 3966	-	expression tag
Arg 3967	-	expression tag
Glu 3968	-	expression tag
Asn 3969	-	expression tag
Leu 3970	-	expression tag
Tyr 3971	-	expression tag
Phe 3972	-	expression tag
Gln 3973	-	expression tag
Gly 3974	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	171703.2
Non-Polymers*	Number of molecules	33
	Total formula weight	250.2
All*	Total formula weight	171953.3

*Water molecules are not included.