4O1V
SPOP Promotes Tumorigenesis by Acting as a Key Regulatory Hub in Kidney Cancer
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Speckle-type POZ protein | polymer | 145 | 16544.0 | 1 | UniProt (O43791) Pfam (PF22486) | Homo sapiens (human) | HIB homolog 1, Roadkill homolog 1 |
| 2 | B (B) | Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN | polymer | 15 | 1475.5 | 1 | UniProt (P60484) | Homo sapiens | Mutated in multiple advanced cancers 1, Phosphatase and tensin homolog |
| 3 | C, D (A, B) | water | water | 18.0 | 105 | Chemie (HOH) |
Sequence modifications
A: 28 - 166 (UniProt: O43791)
| PDB | External Database | Details |
|---|---|---|
| Gly 22 | - | expression tag |
| Ser 23 | - | expression tag |
| Gly 24 | - | expression tag |
| Gly 25 | - | expression tag |
| Ser 26 | - | expression tag |
| Gly 27 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 18019.4 | |
| All* | Total formula weight | 18019.4 |
