4O1V
SPOP Promotes Tumorigenesis by Acting as a Key Regulatory Hub in Kidney Cancer
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 16 |
| Details | BINDING SITE FOR CHAIN B OF PTEN PEPTIDE |
| Chain | Residue |
| A | TYR87 |
| A | HOH253 |
| B | HOH401 |
| B | HOH402 |
| B | HOH403 |
| B | HOH404 |
| B | HOH405 |
| B | HOH406 |
| A | VAL91 |
| A | GLU118 |
| A | TYR123 |
| A | LYS129 |
| A | ASP130 |
| A | TRP131 |
| A | GLY132 |
| A | PHE133 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 1 |
| Details | MOD_RES: Phosphothreonine; by GSK3-beta and PLK3 => ECO:0000269|PubMed:12297295, ECO:0000269|PubMed:20940307, ECO:0007744|PubMed:24275569 |
| Chain | Residue | Details |
| B | THR366 |
Catalytic Information from CSA
