4O1P
Crystal Structure of RNase L in complex with 2-5A and AMP-PNP
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, B, C, D) | Ribonuclease L | polymer | 717 | 81327.8 | 4 | UniProt (A5H025) Pfam (PF12796) Pfam (PF00069) Pfam (PF06479) | Sus scrofa (pig) | |
| 2 | E, I, M, Q (A, B, C, D) | PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER | non-polymer | 506.2 | 4 | Chemie (ANP) | |||
| 3 | F, G, J, K, N... (A, B, C, D) | MAGNESIUM ION | non-polymer | 24.3 | 8 | Chemie (MG) | |||
| 4 | H, L, P, T (A, B, C, D) | [[(2R,3R,4R,5R)-5-(6-aminopurin-9-yl)-4-[[(2R,3R,4R,5R)-5-(6-aminopurin-9-yl)-4-[[(2R,3S,4R,5R)-5-(6-aminopurin-9-yl)-3,4-dihydroxy-oxolan-2-yl]methoxy-hydroxy-phosphoryl]oxy-3-hydroxy-oxolan-2-yl]methoxy-hydroxy-phosphoryl]oxy-3-hydroxy-oxolan-2-yl]methoxy-hydroxy-phosphoryl] phosphono hydrogen phosphate | non-polymer | 1165.6 | 4 | Chemie (25L) | |||
| 5 | U, V, W, X (A, B, C, D) | water | water | 18.0 | 1030 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 21 - 732 (UniProt: A5H025)
| PDB | External Database | Details |
|---|---|---|
| Gly 16 | - | expression tag |
| Ala 17 | - | expression tag |
| Met 18 | - | expression tag |
| Asp 19 | - | expression tag |
| Pro 20 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 325311.3 | |
| Non-Polymers* | Number of molecules | 16 |
| Total formula weight | 6881.6 | |
| All* | Total formula weight | 332192.9 |
