4O1F

Structure of a methyltransferase component in complex with THF involved in O-demethylation

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	Dihydropteroate synthase DHPS	polymer	290	31755.5	2	UniProt (B8FW00) Pfam (PF00809)	Desulfitobacterium hafniense (DCB-2 DCB-2)
2	C, D (A, B)	(6S)-5,6,7,8-TETRAHYDROFOLATE	non-polymer		445.4	2	Chemie (THG)
3	E, F (A, B)	water	water		18.0	270	Chemie (HOH)

Sequence modifications

A, B: 3 - 270 (UniProt: B8FW00)

PDB	External Database	Details
Met -19	-	expression tag
Gly -18	-	expression tag
Ser -17	-	expression tag
Ser -16	-	expression tag
His -15	-	expression tag
His -14	-	expression tag
His -13	-	expression tag
His -12	-	expression tag
His -11	-	expression tag
His -10	-	expression tag
Ser -9	-	expression tag
Ser -8	-	expression tag
Gly -7	-	expression tag
Leu -6	-	expression tag
Val -5	-	expression tag
Pro -4	-	expression tag
Arg -3	-	expression tag
Gly -2	-	expression tag
Ser -1	-	expression tag
His 0	-	expression tag
Met 1	-	expression tag
Leu 2	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	63511.0
Non-Polymers*	Number of molecules	2
	Total formula weight	890.9
All*	Total formula weight	64401.8

*Water molecules are not included.