4O1F

Structure of a methyltransferase component in complex with THF involved in O-demethylation

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0005829	cellular_component	cytosol
A	0008168	molecular_function	methyltransferase activity
A	0008705	molecular_function	methionine synthase activity
A	0009086	biological_process	methionine biosynthetic process
A	0032259	biological_process	methylation
A	0042558	biological_process	pteridine-containing compound metabolic process
A	0044237	biological_process	cellular metabolic process
B	0005829	cellular_component	cytosol
B	0008168	molecular_function	methyltransferase activity
B	0008705	molecular_function	methionine synthase activity
B	0009086	biological_process	methionine biosynthetic process
B	0032259	biological_process	methylation
B	0042558	biological_process	pteridine-containing compound metabolic process
B	0044237	biological_process	cellular metabolic process

Functional Information from PDB Data

site_id	AC1
Number of Residues	15
Details	BINDING SITE FOR RESIDUE THG A 3000

Chain	Residue
A	GLU7
A	ASP229
A	ASN232
A	HOH3143
A	HOH3214
A	HOH3215
A	HOH3216
A	LYS8
A	ILE13
A	ASP76
A	ASN97
A	ASP161
A	GLY196
A	LYS208
A	ILE227

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site_id	AC2
Number of Residues	17
Details	BINDING SITE FOR RESIDUE THG B 4000

Chain	Residue
B	GLU7
B	LYS8
B	ILE13
B	ASP76
B	ASN97
B	ASP161
B	GLY196
B	LYS208
B	ILE227
B	ASP229
B	ASN232
B	HOH4138
B	HOH4170
B	HOH4237
B	HOH4248
B	HOH4249
B	HOH4251

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