4O0F
Crystal structure of the human L-asparaginase protein T219A mutant
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B | Isoaspartyl peptidase/L-asparaginase | polymer | 309 | 32202.6 | 2 | UniProt (Q7L266) Pfam (PF01112) In PDB | Homo sapiens (human) | Asparaginase-like protein 1, Beta-aspartyl-peptidase, Isoaspartyl dipeptidase, L-asparagine amidohydrolase, Isoaspartyl peptidase/L-asparaginase alpha chain, Isoaspartyl peptidase/L-asparaginase beta chain |
| 2 | A, B | SODIUM ION | non-polymer | 23.0 | 4 | Chemie (NA) | |||
| 3 | A, B | GLYCINE | non-polymer | 75.1 | 4 | Chemie (GLY) | |||
| 4 | water | water | 18.0 | 155 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 308 (UniProt: Q7L266)
| PDB | External Database | Details |
|---|---|---|
| His 0 | - | expression tag |
| Ala 219 | Thr 219 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 64405.2 | |
| Non-Polymers* | Number of molecules | 8 |
| Total formula weight | 392.2 | |
| All* | Total formula weight | 64797.5 |
