4NZR

Crystal structure of the antibody-binding region of Protein M (Protein M TD) in complex with anti-HIV antibody PGT135 Fab

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	H	PGT135 heavy chain	polymer	234	25385.6	1		Homo sapiens (human)
2	L	PGT135 light chain	polymer	214	23795.5	1		Homo sapiens (human)
3	M	Protein M TD	polymer	416	46972.7	1	UniProt (P47523) Pfam (PF20757) Pfam (PF22805) In PDB	Mycoplasma genitalium	protein MG281
4	M	GLYCEROL	non-polymer		92.1	1	Chemie (GOL)
5		water	water		18.0	865	Chemie (HOH)

Sequence modifications

M: 74 - 468 (UniProt: P47523)

PDB	External Database	Details
Met 53	-	expression tag
Gly 54	-	expression tag
Ser 55	-	expression tag
Ser 56	-	expression tag
His 57	-	expression tag
His 58	-	expression tag
His 59	-	expression tag
His 60	-	expression tag
His 61	-	expression tag
His 62	-	expression tag
Ser 63	-	expression tag
Ser 64	-	expression tag
Gly 65	-	expression tag
Leu 66	-	expression tag
Val 67	-	expression tag
Pro 68	-	expression tag
Arg 69	-	expression tag
Gly 70	-	expression tag
Ser 71	-	expression tag
His 72	-	expression tag
Met 73	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	3
	Total formula weight	96153.7
Non-Polymers*	Number of molecules	1
	Total formula weight	92.1
All*	Total formula weight	96245.8

*Water molecules are not included.