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4NXZ

DNA polymerase beta with O6mG in the template base opposite to incoming non-hydrolyzable TTP with manganese in the active site

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(T)
5'-D(*CP*CP*GP*AP*CP*(6OG)P*TP*CP*GP*CP*AP*TP*CP*AP*GP*C)-3'polymer164858.21
2B
(P)
5'-D(*GP*CP*TP*GP*AP*TP*GP*CP*GP*A)-3'polymer103085.01
3C
(D)
5'-D(P*GP*TP*CP*GP*G)-3'polymer51536.01
4D
(A)
DNA polymerase betapolymer32637182.41UniProt (P06746)
Pfam (PF14716)
Pfam (PF10391)
Pfam (PF14792)
Pfam (PF14791)
Homo sapiens (human)
5E, F
(A)
MANGANESE (II) IONnon-polymer54.92Chemie (MN)
6G, H
(A)
SODIUM IONnon-polymer23.02Chemie (NA)
7I
(A)
5'-O-[(R)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]thymidinenon-polymer481.21Chemie (1FZ)
8J, K, L, M
(T, P, D, A)
waterwater18.076Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains4
Total formula weight46661.6
Non-Polymers*Number of molecules5
Total formula weight637.0
All*Total formula weight47298.7
*Water molecules are not included.

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PDB entries from 2025-06-11

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