4NXQ
Crystal Structure of T-cell Lymphoma Invasion and Metastasis-1 PDZ Domain Quadruple Mutant (QM) in Complex With Caspr4 Peptide
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C | T-lymphoma invasion and metastasis-inducing protein 1 | polymer | 94 | 10192.4 | 3 | UniProt (Q13009) Pfam (PF00595) In PDB | Homo sapiens (human) | TIAM-1 |
| 2 | D, E, F | Contactin-associated protein-like 4 peptide | polymer | 8 | 1105.2 | 3 | UniProt (Q9C0A0) In PDB | Homo sapiens | Caspr4 peptide |
| 3 | water | water | 18.0 | 160 | Chemie (HOH) |
Sequence modifications
A, B, C: 841 - 930 (UniProt: Q13009)
| PDB | External Database | Details |
|---|---|---|
| Gly 837 | - | expression tag |
| Ala 838 | - | expression tag |
| Met 839 | - | expression tag |
| Gly 840 | - | expression tag |
| His 844 | Gln 844 | variant |
| Met 911 | Leu 911 | engineered mutation |
| Glu 912 | Lys 912 | engineered mutation |
| Phe 915 | Leu 915 | engineered mutation |
| Val 920 | Leu 920 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 6 |
| Total formula weight | 33892.7 | |
| All* | Total formula weight | 33892.7 |
