4NWC
Crystal structure of the GluK3 ligand-binding domain (S1S2) in complex with the agonist (2S,4R)-4-(3-Methoxy-3-oxopropyl)glutamic acid at 2.01 A resolution.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Glutamate receptor ionotropic, kainate 3 | polymer | 258 | 29092.5 | 1 | UniProt (P42264) Pfam (PF10613) Pfam (PF00060) | Rattus norvegicus (brown rat rat rats) | GluK3, Glutamate receptor 7, GluR-7, GluR7 |
| 2 | B, C (A) | POTASSIUM ION | non-polymer | 39.1 | 2 | Chemie (K) | |||
| 3 | D (A) | PHOSPHATE ION | non-polymer | 95.0 | 1 | Chemie (PO4) | |||
| 4 | E (A) | CHLORIDE ION | non-polymer | 35.5 | 1 | Chemie (CL) | |||
| 5 | F (A) | (2S,4R)-4-(3-Methoxy-3-oxopropyl) glutamic acid | non-polymer | 233.2 | 1 | Chemie (2QE) | |||
| 6 | G (A) | water | water | 18.0 | 230 | Chemie (HOH) |
Sequence modifications
A: 432 - 546 (UniProt: P42264)
A: 669 - 806 (UniProt: P42264)
| PDB | External Database | Details |
|---|---|---|
| Gly 429 | - | expression tag |
| Pro 430 | - | expression tag |
| Gly 431 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Gly 547 | - | linker |
| Thr 548 | - | linker |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 29092.5 | |
| Non-Polymers* | Number of molecules | 5 |
| Total formula weight | 441.8 | |
| All* | Total formula weight | 29534.3 |
