4NW7
PDE4 catalytic domain
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | polymer | 372 | 42813.2 | 1 | UniProt (Q07343) Pfam (PF00233) In PDB | Homo sapiens (human) | DPDE4, PDE32 |
| 2 | A | ZINC ION | non-polymer | 65.4 | 1 | Chemie (ZN) | |||
| 3 | A | MAGNESIUM ION | non-polymer | 24.3 | 1 | Chemie (MG) | |||
| 4 | A | SODIUM ION | non-polymer | 23.0 | 1 | Chemie (NA) | |||
| 5 | A | (4-{[4-(3-chlorophenyl)-6-cyclopropyl-1,3,5-triazin-2-yl]amino}phenyl)acetic acid | non-polymer | 380.8 | 1 | Chemie (2O5) | |||
| 6 | A | 1,2-ETHANEDIOL | non-polymer | 62.1 | 6 | Chemie (EDO) | |||
| 7 | water | water | 18.0 | 193 | Chemie (HOH) |
Sequence modifications
A: 324 - 691 (UniProt: Q07343)
| PDB | External Database | Details |
|---|---|---|
| Gly 320 | - | expression tag |
| Ser 321 | - | expression tag |
| His 322 | - | expression tag |
| Met 323 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 42813.2 | |
| Non-Polymers* | Number of molecules | 10 |
| Total formula weight | 865.9 | |
| All* | Total formula weight | 43679.1 |
