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4NVP

Structure of the cyclic nucleotide-binding domain of HCN4 channel complexed with 7-CH-cAMP

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4polymer20924498.01UniProt (Q9Y3Q4)
Pfam (PF00027)
Homo sapiens (human)
2B
(A)
(2S,4aR,6R,7R,7aS)-6-(4-amino-7H-pyrrolo[2,3-d]pyrimidin-7-yl)tetrahydro-4H-furo[3,2-d][1,3,2]dioxaphosphinine-2,7-diol 2-oxidenon-polymer328.21Chemie (7CH)
3C
(A)
waterwater18.037Chemie (HOH)
Sequence modifications
A: 521 - 723 (UniProt: Q9Y3Q4)
PDBExternal DatabaseDetails
Gly 515-expression tag
Pro 516-expression tag
Ser 517-expression tag
Ser 518-expression tag
Pro 519-expression tag
Met 520-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight24498.0
Non-Polymers*Number of molecules1
Total formula weight328.2
All*Total formula weight24826.2
*Water molecules are not included.

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PDB entries from 2025-07-23

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