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4NUS

Rsk2 N-terminal kinase in complex with LJH685

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1ARibosomal protein S6 kinase alpha-3polymer32337205.01UniProt (P51812)
Pfam (PF00069)
In PDB
Homo sapiens (human)S6K-alpha-3, 90 kDa ribosomal protein S6 kinase 3, p90-RSK 3, p90RSK3, Insulin-stimulated protein kinase 1, ISPK-1, MAP kinase-activated protein kinase 1b, MAPK-activated protein kinase 1b, MAPKAP kinase 1b, MAPKAPK-1b, Ribosomal S6 kinase 2, RSK-2, pp90RSK2
2A2,6-difluoro-4-{4-[4-(4-methylpiperazin-1-yl)phenyl]pyridin-3-yl}phenolnon-polymer381.41Chemie (2NK)
3waterwater18.050Chemie (HOH)
Sequence modifications
A: 39 - 359 (UniProt: P51812)
PDBExternal DatabaseDetails
Gly 37-expression tag
Pro 38-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight37205.0
Non-Polymers*Number of molecules1
Total formula weight381.4
All*Total formula weight37586.4
*Water molecules are not included.

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PDB entries from 2024-04-24

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