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4NT0

Crystal structure of orotidine 5'-monophosphate decarboxylase from Methanobacterium thermoautotrophicum complexed with 3-deazauridine 5'-monophosphate

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B
(A, B)
Orotidine 5'-phosphate decarboxylasepolymer22824884.72UniProt (O26232)
Pfam (PF00215)
Methanothermobacter thermautotrophicusOMP decarboxylase, OMPDCase, OMPdecase
2C, F
(A, B)
4-hydroxy-1-(5-O-phosphono-beta-D-ribofuranosyl)pyridin-2(1H)-onenon-polymer323.22Chemie (3DU)
3D, G
(A, B)
CALCIUM IONnon-polymer40.12Chemie (CA)
4E
(A)
DI(HYDROXYETHYL)ETHERnon-polymer106.11Chemie (PEG)
5H, I
(A, B)
waterwater18.0139Chemie (HOH)
Sequence modifications
A, B: 1 - 228 (UniProt: O26232)
PDBExternal DatabaseDetails
Pro 101Arg 101engineered mutation
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight49769.4
Non-Polymers*Number of molecules5
Total formula weight832.7
All*Total formula weight50602.1
*Water molecules are not included.

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PDB entries from 2025-06-18

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