4NRT

Human Norovirus polymerase bound to Compound 6 (suramin derivative)

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	hNV-RdRp	polymer	526	58657.8	1	UniProt (A0ZNP5) Pfam (PF00680) In PDB	Norwalk-like virus
2	A	4-({4-methyl-3-[(3-nitrobenzoyl)amino]benzoyl}amino)naphthalene-1,5-disulfonic acid	non-polymer		585.6	1	Chemie (2NG)
3		water	water		18.0	494	Chemie (HOH)

Sequence modifications

A: 1 - 510 (UniProt: A0ZNP5)

PDB	External Database	Details
Met 0	-	expression tag
Gly 153	Glu 1342	conflict
Val 211	Ile 1400	conflict
Val 511	-	expression tag
Asp 512	-	expression tag
Lys 513	-	expression tag
Leu 514	-	expression tag
Ala 515	-	expression tag
Ala 516	-	expression tag
Ala 517	-	expression tag
Leu 518	-	expression tag
Glu 519	-	expression tag
His 520	-	expression tag
His 521	-	expression tag
His 522	-	expression tag
His 523	-	expression tag
His 524	-	expression tag
His 525	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	58657.8
Non-Polymers*	Number of molecules	1
	Total formula weight	585.6
All*	Total formula weight	59243.3

*Water molecules are not included.