4NQN
Crystal Structure of the bromodomain of human BRD9 in complex with a triazolo-phthalazine ligand
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Bromodomain-containing protein 9 | polymer | 123 | 14249.8 | 1 | UniProt (C9JBY0) Pfam (PF00439) UniProt (by SIFTS) (Q9H8M2) | Homo sapiens (human) | |
| 2 | B (A) | 2-chloro-N-[5-(3-methyl[1,2,4]triazolo[3,4-a]phthalazin-6-yl)-2-(morpholin-4-yl)phenyl]benzenesulfonamide | non-polymer | 535.0 | 1 | Chemie (Y1Z) | |||
| 3 | C (A) | water | water | 18.0 | 158 | Chemie (HOH) |
Sequence modifications
A: 14 - 134 (UniProt: C9JBY0)
| PDB | External Database | Details |
|---|---|---|
| Ser 12 | - | expression tag |
| Met 13 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 14249.8 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 535.0 | |
| All* | Total formula weight | 14784.8 |
