4NOS
HUMAN INDUCIBLE NITRIC OXIDE SYNTHASE WITH INHIBITOR
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, B, C, D) | INDUCIBLE NITRIC OXIDE SYNTHASE | polymer | 427 | 49461.4 | 4 | UniProt (P35228) Pfam (PF02898) | Homo sapiens (human) | INOS, NOS2 |
| 2 | E, L (A, C) | ZINC ION | non-polymer | 65.4 | 2 | Chemie (ZN) | |||
| 3 | F, I, M, P (A, B, C, D) | PROTOPORPHYRIN IX CONTAINING FE | non-polymer | 616.5 | 4 | Chemie (HEM) | |||
| 4 | G (A) | 2-AMINO-6-(1,2-DIHYDROXY-PROPYL)-7,8-DIHYDRO-6H-PTERIDIN-4-ONE | non-polymer | 239.2 | 1 | Chemie (H2B) | |||
| 5 | H, K, O, R (A, B, C, D) | ETHYLISOTHIOUREA | non-polymer | 104.2 | 4 | Chemie (ITU) | |||
| 6 | J, N, Q (B, C, D) | 5,6,7,8-TETRAHYDROBIOPTERIN | non-polymer | 241.2 | 3 | Chemie (H4B) | |||
| 7 | S, T, U, V (A, B, C, D) | water | water | 18.0 | 1371 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 82 - 508 (UniProt: P35228)
| PDB | External Database | Details |
|---|---|---|
| Ile 423 | Leu 423 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 197845.5 | |
| Non-Polymers* | Number of molecules | 14 |
| Total formula weight | 3976.4 | |
| All* | Total formula weight | 201821.9 |
