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4NNI

Structural basis for targeting the ribosomal protein S1 of Mycobacterium tuberculosis by pyrazinamide

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B
(A, B)
30S ribosomal protein S1polymer16118583.82UniProt (P9WH43)
Pfam (PF00575)
Mycobacterium tuberculosis
2C, D, E, F
(A, B)
PYRAZINE-2-CARBOXYLIC ACIDnon-polymer124.14Chemie (VGL)
3G, H
(A, B)
waterwater18.037Chemie (HOH)
Sequence modifications
A, B: 285 - 438 (UniProt: P9WH43)
PDBExternal DatabaseDetails
Asn 278-expression tag
Leu 279-expression tag
Tyr 280-expression tag
Phe 281-expression tag
Gln 282-expression tag
His 283-expression tag
Met 284-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight37167.5
Non-Polymers*Number of molecules4
Total formula weight496.4
All*Total formula weight37663.9
*Water molecules are not included.

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PDB entries from 2026-02-25

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