4NMX

PCSK9(deltaCRD) in complex with phage-derived inhibitory peptide 2-8

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	Proprotein convertase subtilisin/kexin type 9	polymer	125	14006.7	1	UniProt (Q8NBP7) Pfam (PF05922)	Homo sapiens (human)	Neural apoptosis-regulated convertase 1, NARC-1, Proprotein convertase 9, PC9, Subtilisin/kexin-like protease PC9
2	B (B)	Proprotein convertase subtilisin/kexin type 9	polymer	308	32836.9	1	UniProt (Q8NBP7) Pfam (PF00082)	Homo sapiens (human)	Neural apoptosis-regulated convertase 1, NARC-1, Proprotein convertase 9, PC9, Subtilisin/kexin-like protease PC9
3	C (Z)	peptide 2-8	polymer	15	1698.8	1
4	D, E, F (A, B, Z)	water	water		18.0	378	Chemie (HOH)

Sequence modifications

A: 31 - 152 (UniProt: Q8NBP7)

PDB	External Database	Details
Ala 28	-	expression tag
Gly 29	-	expression tag
Ser 30	-	expression tag

B: 153 - 452 (UniProt: Q8NBP7)

PDB	External Database	Details
Asn 453	-	expression tag
Ser 454	-	expression tag
His 455	-	expression tag
His 456	-	expression tag
His 457	-	expression tag
His 458	-	expression tag
His 459	-	expression tag
His 460	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	3
	Total formula weight	48542.4
All*	Total formula weight	48542.4

*Water molecules are not included.