4NM3
Crystal structure of GSK-3/Axin complex bound to phosphorylated N-terminal auto-inhibitory pS9 peptide
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | Glycogen synthase kinase-3 beta | polymer | 389 | 44260.6 | 1 | UniProt (P49841) Pfam (PF00069) In PDB | Homo sapiens (human) | GSK-3 beta, Serine/threonine-protein kinase GSK3B |
2 | B | Axin-1 | polymer | 24 | 2738.1 | 1 | UniProt (O15169) In PDB | Homo sapiens (human) | Axis inhibition protein 1, hAxin |
3 | A | GLYCEROL | non-polymer | 92.1 | 4 | Chemie (GOL) | |||
4 | A | MAGNESIUM ION | non-polymer | 24.3 | 2 | Chemie (MG) | |||
5 | A | CHLORIDE ION | non-polymer | 35.5 | 1 | Chemie (CL) | |||
6 | A | 2,3-DIHYDROXY-1,4-DITHIOBUTANE | non-polymer | 154.3 | 1 | Chemie (DTT) | |||
7 | A | ADENOSINE-5'-DIPHOSPHATE | non-polymer | 427.2 | 1 | Chemie (ADP) | |||
8 | water | water | 18.0 | 197 | Chemie (HOH) |
Sequence modifications
A: 1 - 383 (UniProt: P49841)
B: 383 - 402 (UniProt: O15169)
PDB | External Database | Details |
---|---|---|
His 384 | - | expression tag |
His 385 | - | expression tag |
His 386 | - | expression tag |
His 387 | - | expression tag |
His 388 | - | expression tag |
His 389 | - | expression tag |
PDB | External Database | Details |
---|---|---|
Gly 379 | - | expression tag |
Gly 380 | - | expression tag |
Ile 381 | - | expression tag |
Leu 382 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 2 |
Total formula weight | 46998.7 | |
Non-Polymers* | Number of molecules | 9 |
Total formula weight | 1033.9 | |
All* | Total formula weight | 48032.6 |