4NL9

Crystal structure of the human Anks3-SAM/Anks6-SAM heterodimer

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	Ankyrin repeat and SAM domain-containing protein 3	polymer	71	8050.2	2	UniProt (Q6ZW76) Pfam (PF00536)	Homo sapiens (human)
2	C, D (C, D)	Ankyrin repeat and SAM domain-containing protein 6	polymer	71	7892.8	2	UniProt (Q68DC2) Pfam (PF00536)	Homo sapiens (human)	Ankyrin repeat domain-containing protein 14, SamCystin, Sterile alpha motif domain-containing protein 6, SAM domain-containing protein 6
3	E (D)	MAGNESIUM ION	non-polymer		24.3	1	Chemie (MG)
4	F, G, H, I (A, B, C, D)	water	water		18.0	246	Chemie (HOH)

Sequence modifications

A, B: 2 - 71 (UniProt: Q6ZW76)

PDB	External Database	Details
Ser 1	-	expression tag
Glu 36	Ile 455	engineered mutation

C, D: 2 - 71 (UniProt: Q68DC2)

PDB	External Database	Details
Ser 1	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	31886.0
Non-Polymers*	Number of molecules	1
	Total formula weight	24.3
All*	Total formula weight	31910.3

*Water molecules are not included.