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4NKQ

Structure of a Cytokine Receptor Complex

Replaces:  3CXE
Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
Cytokine receptor common subunit betapolymer41447258.81UniProt (P32927)
Pfam (PF21460)
Homo sapiens (human)CDw131, GM-CSF/IL-3/IL-5 receptor common beta subunit
2B
(C)
Granulocyte-macrophage colony-stimulating factorpolymer12714492.51UniProt (P04141)
Pfam (PF01109)
Homo sapiens (human)GM-CSF, Colony-stimulating factor, CSF, Molgramostin, Sargramostim
3C
(B)
Granulocyte-macrophage colony-stimulating factor receptor subunit alphapolymer30534850.51UniProt (P15509)
Pfam (PF09240)
Homo sapiens (human)GM-CSF-R-alpha, GMCSFR-alpha, GMR-alpha, CDw116
4D, E, F, G
(A, B)
2-acetamido-2-deoxy-beta-D-glucopyranosenon-polymer221.24Chemie (NAG)
Sequence modifications
A: 25 - 438 (UniProt: P32927)
PDBExternal DatabaseDetails
Gln 346Asn 346engineered mutation
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains3
Total formula weight96601.7
Non-Polymers*Number of molecules4
Total formula weight884.8
All*Total formula weight97486.6
*Water molecules are not included.

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PDB entries from 2024-11-06

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