4NKK
Crystal structure of a multi-drug resistant clinical isolate-769 HIV-1 protease variant that is resistant to the dimerization inhibitory activity of TLF-PafF
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | HIV-1 protease | polymer | 99 | 10725.6 | 1 | UniProt (Q000H7) Pfam (PF00077) In PDB | Human immunodeficiency virus 1 | |
| 2 | water | water | 18.0 | 142 | Chemie (HOH) |
Sequence modifications
A: 1 - 99 (UniProt: Q000H7)
| PDB | External Database | Details |
|---|---|---|
| Val 10 | Ile 10 | engineered mutation |
| Asn 25 | Asp 25 | engineered mutation |
| Glu 35 | Asp 35 | SEE REMARK 999 |
| Val 36 | Ile 36 | SEE REMARK 999 |
| Leu 46 | Met 46 | SEE REMARK 999 |
| Ala 82 | Thr 82 | SEE REMARK 999 |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 10725.6 | |
| All* | Total formula weight | 10725.6 |
