4NHK
Crystal structure of Tpa1p from Saccharomyces cerevisiae, termination and polyadenylation protein 1, in complex with pyridine-2,4-dicarboxylic acid (2,4-PDCA)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | PKHD-type hydroxylase TPA1 | polymer | 647 | 74494.5 | 1 | UniProt (P40032) Pfam (PF10637) | Saccharomyces cerevisiae (Baker's yeast) | Termination and polyadenylation protein 1 |
| 2 | B (A) | MANGANESE (II) ION | non-polymer | 54.9 | 1 | Chemie (MN) | |||
| 3 | C (A) | PYRIDINE-2,4-DICARBOXYLIC ACID | non-polymer | 167.1 | 1 | Chemie (PD2) | |||
| 4 | D, E, F, G (A) | GLYCEROL | non-polymer | 92.1 | 4 | Chemie (GOL) | |||
| 5 | H (A) | water | water | 18.0 | 359 | Chemie (HOH) |
Sequence modifications
A: 21 - 644 (UniProt: P40032)
| PDB | External Database | Details |
|---|---|---|
| Met -2 | - | expression tag |
| His -1 | - | expression tag |
| His 0 | - | expression tag |
| His 1 | - | expression tag |
| His 2 | - | expression tag |
| His 3 | - | expression tag |
| His 4 | - | expression tag |
| Ser 5 | - | expression tag |
| Ser 6 | - | expression tag |
| Gly 7 | - | expression tag |
| Val 8 | - | expression tag |
| Asp 9 | - | expression tag |
| Leu 10 | - | expression tag |
| Gly 11 | - | expression tag |
| Thr 12 | - | expression tag |
| Glu 13 | - | expression tag |
| Asn 14 | - | expression tag |
| Leu 15 | - | expression tag |
| Tyr 16 | - | expression tag |
| Phe 17 | - | expression tag |
| Gln 18 | - | expression tag |
| Ser 19 | - | expression tag |
| Met 20 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 74494.5 | |
| Non-Polymers* | Number of molecules | 6 |
| Total formula weight | 590.4 | |
| All* | Total formula weight | 75085.0 |






