4NGF
Structure of human Dicer Platform-PAZ-Connector Helix cassette in complex with 17-mer siRNA having 5'-p and UU-3' ends (3.1 Angstrom resolution)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, B, C, D) | Endoribonuclease Dicer | polymer | 302 | 35044.5 | 4 | UniProt (Q9UPY3) Pfam (PF20931) Pfam (PF02170) | Homo sapiens (human) | Helicase with RNase motif, Helicase MOI |
| 2 | E, F, G, H (E, F, G, H) | 5'-R(P*UP*CP*GP*AP*AP*GP*GP*UP*CP*CP*UP*UP*CP*GP*UP*UP*U)-3' | polymer | 17 | 5358.2 | 4 |
Sequence modifications
A, B, C, D: 755 - 1055 (UniProt: Q9UPY3)
| PDB | External Database | Details |
|---|---|---|
| Ser 754 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 8 |
| Total formula weight | 161610.8 | |
| All* | Total formula weight | 161610.8 |
