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4NGF

Structure of human Dicer Platform-PAZ-Connector Helix cassette in complex with 17-mer siRNA having 5'-p and UU-3' ends (3.1 Angstrom resolution)

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B, C, DEndoribonuclease Dicerpolymer30235044.54UniProt (Q9UPY3)
Pfam (PF20931)
Pfam (PF02170)
In PDB
Homo sapiens (human)Helicase with RNase motif, Helicase MOI
2E, F, G, H5'-R(P*UP*CP*GP*AP*AP*GP*GP*UP*CP*CP*UP*UP*CP*GP*UP*UP*U)-3'polymer175358.24
Sequence modifications
A, B, C, D: 755 - 1055 (UniProt: Q9UPY3)
PDBExternal DatabaseDetails
Ser 754-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains8
Total formula weight161610.8
All*Total formula weight161610.8
*Water molecules are not included.

223166

PDB entries from 2024-07-31

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