4NEW
Crystal structure of Trypanothione Reductase from Trypanosoma cruzi in complex with inhibitor EP127 (5-{5-[1-(PYRROLIDIN-1-YL)CYCLOHEXYL]-1,3-THIAZOL-2-YL}-1H-INDOLE)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Trypanothione reductase, putative | polymer | 492 | 53935.7 | 1 | UniProt (K4E0T9) | Trypanosoma cruzi | |
| 2 | B (A) | FLAVIN-ADENINE DINUCLEOTIDE | non-polymer | 785.5 | 1 | Chemie (FAD) | |||
| 3 | C (A) | 5-{5-[1-(pyrrolidin-1-yl)cyclohexyl]-1,3-thiazol-2-yl}-1H-indole | non-polymer | 351.5 | 1 | Chemie (2JR) |
Sequence modifications
A: 1 - 492 (UniProt: K4E0T9)
| PDB | External Database | Details |
|---|---|---|
| Asn 95 | Lys 95 | SEE REMARK 999 |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 53935.7 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 1137.1 | |
| All* | Total formula weight | 55072.8 |
