4NEC
Conversion of a Disulfide Bond into a Thioacetal Group during Echinomycin Biosynthesis
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B, C, D | Putative SAM-dependent methyltransferase | polymer | 264 | 28509.7 | 4 | UniProt (Q0X0A7) Pfam (PF13649) In PDB | Streptomyces lasaliensis | |
2 | E, F, G, H | Echinomycin | polymer | 8 | 809.0 | 4 | NOR (NOR01126) BIRD (PRD_000491) | Streptomyces echinatus | |
3 | A, B, C, D | S-ADENOSYL-L-HOMOCYSTEINE | non-polymer | 384.4 | 4 | Chemie (SAH) | |||
4 | A, D | TRIETHYLENE GLYCOL | non-polymer | 150.2 | 2 | Chemie (PGE) | |||
5 | A, C | SODIUM ION | non-polymer | 23.0 | 3 | Chemie (NA) | |||
6 | H, E, F, G | 2-CARBOXYQUINOXALINE | non-polymer | 174.2 | 8 | BIRD (PRD_000491) Chemie (QUI) | |||
7 | B | ACETATE ION | non-polymer | 59.0 | 1 | Chemie (ACT) | |||
8 | D | POLYETHYLENE GLYCOL (N=34) | non-polymer | 1529.8 | 2 | Chemie (15P) | |||
9 | water | water | 18.0 | 320 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 1 - 224 (UniProt: Q0X0A7)
PDB | External Database | Details |
---|---|---|
Met -19 | - | expression tag |
Gly -18 | - | expression tag |
Ser -17 | - | expression tag |
Ser -16 | - | expression tag |
His -15 | - | expression tag |
His -14 | - | expression tag |
His -13 | - | expression tag |
His -12 | - | expression tag |
His -11 | - | expression tag |
His -10 | - | expression tag |
Ser -9 | - | expression tag |
Ser -8 | - | expression tag |
Gly -7 | - | expression tag |
Leu -6 | - | expression tag |
Val -5 | - | expression tag |
Pro -4 | - | expression tag |
Arg -3 | - | expression tag |
Gly -2 | - | expression tag |
Ser -1 | - | expression tag |
His 0 | - | expression tag |
Trp 225 | - | expression tag |
Asn 226 | - | expression tag |
Ser 227 | - | expression tag |
Ser 228 | - | expression tag |
Ser 229 | - | expression tag |
Val 230 | - | expression tag |
Asp 231 | - | expression tag |
Lys 232 | - | expression tag |
Leu 233 | - | expression tag |
Ala 234 | - | expression tag |
Ala 235 | - | expression tag |
Ala 236 | - | expression tag |
Leu 237 | - | expression tag |
Glu 238 | - | expression tag |
His 239 | - | expression tag |
His 240 | - | expression tag |
His 241 | - | expression tag |
His 242 | - | expression tag |
His 243 | - | expression tag |
His 244 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 8 |
Total formula weight | 117274.8 | |
Non-Polymers* | Number of molecules | 20 |
Total formula weight | 6418.9 | |
All* | Total formula weight | 123693.7 |