4ND3
Crystal structure of the lactate dehydrogenase from cryptosporidium parvum complexed with substrate (l-lactic acid) and cofactor (b-nicotinamide adenine dinucleotide)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B | Lactate dehydrogenase, adjacent gene encodes predicted malate dehydrogenase | polymer | 321 | 33884.9 | 2 | UniProt (Q5CYZ2) Pfam (PF00056) Pfam (PF02866) In PDB | Cryptosporidium parvum | |
| 2 | A, B | NICOTINAMIDE-ADENINE-DINUCLEOTIDE | non-polymer | 663.4 | 2 | Chemie (NAD) | |||
| 3 | A | (2S)-2-HYDROXYPROPANOIC ACID | non-polymer | 90.1 | 1 | Chemie (2OP) | |||
| 4 | A, B | GLYCEROL | non-polymer | 92.1 | 3 | Chemie (GOL) | |||
| 5 | water | water | 18.0 | 206 | Chemie (HOH) |
Sequence modifications
A, B: 17 - 337 (UniProt: Q5CYZ2)
| PDB | External Database | Details |
|---|---|---|
| Ala 202 | Val 200 | SEE REMARK 999 |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 67769.7 | |
| Non-Polymers* | Number of molecules | 6 |
| Total formula weight | 1693.2 | |
| All* | Total formula weight | 69462.9 |
