4NCM
Influenza polymerase basic protein 2 (PB2) bound to a small-molecule inhibitor
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | Polymerase basic protein 2 | polymer | 169 | 19174.3 | 1 | UniProt (P31345) Pfam (PF00604) In PDB | Influenza A virus | RNA-directed RNA polymerase subunit P3 |
| 2 | A | N~2~-[2-(5-chloro-1H-pyrrolo[2,3-b]pyridin-3-yl)-5-fluoropyrimidin-4-yl]-N,N-dimethyl-L-alaninamide | non-polymer | 362.8 | 1 | Chemie (704) | |||
| 3 | water | water | 18.0 | 27 | Chemie (HOH) |
Sequence modifications
A: 317 - 483 (UniProt: P31345)
| PDB | External Database | Details |
|---|---|---|
| Gly 315 | - | expression tag |
| His 316 | - | expression tag |
| Met 317 | Leu 317 | conflict |
| Lys 389 | Arg 389 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 19174.3 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 362.8 | |
| All* | Total formula weight | 19537.1 |
