4NB6
Crystal structure of the ligand binding domain of RORC with T0901317
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Nuclear receptor ROR-gamma | polymer | 251 | 29041.5 | 2 | UniProt (P51449) Pfam (PF00104) | Homo sapiens (human) | Nuclear receptor RZR-gamma, Nuclear receptor subfamily 1 group F member 3, Retinoid-related orphan receptor-gamma |
| 2 | C, D (A, B) | N-(2,2,2-TRIFLUOROETHYL)-N-{4-[2,2,2-TRIFLUORO-1-HYDROXY-1-(TRIFLUOROMETHYL)ETHYL]PHENYL}BENZENESULFONAMIDE | non-polymer | 481.3 | 2 | Chemie (444) | |||
| 3 | E, F (A, B) | water | water | 18.0 | 2 | Chemie (HOH) |
Sequence modifications
A, B: 241 - 486 (UniProt: P51449)
| PDB | External Database | Details |
|---|---|---|
| Gly 239 | - | expression tag |
| Ser 240 | - | expression tag |
| Gly 487 | - | expression tag |
| Asn 488 | - | expression tag |
| Ser 489 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 58083.1 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 962.7 | |
| All* | Total formula weight | 59045.8 |
