4N9L

crystal structure of beta-lactamse PenP_E166S in complex with meropenem

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	B, A	Beta-lactamase	polymer	268	29785.8	2	UniProt (P00808) Pfam (PF00144) In PDB	Bacillus licheniformis	Penicillinase
2	B, A	(2S,3R,4S)-4-{[(3S,5S)-5-(dimethylcarbamoyl)pyrrolidin-3-yl]sulfanyl}-2-[(2S,3R)-3-hydroxy-1-oxobutan-2-yl]-3-methyl-3,4-dihydro-2H-pyrrole-5-carboxylic acid	non-polymer		385.5	2	Chemie (DWZ)
3		water	water		18.0	314	Chemie (HOH)

Sequence modifications

B, A: 26 - 295 (UniProt: P00808)

PDB	External Database	Details
Gly 23	-	expression tag
Pro 24	-	expression tag
Met 25	-	expression tag
Ser 166	Glu 180	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	59571.5
Non-Polymers*	Number of molecules	2
	Total formula weight	771.0
All*	Total formula weight	60342.5

*Water molecules are not included.