4N8R
Crystal structure of RXRa LBD complexed with a synthetic modulator K-8008
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, B, C, D) | Retinoic acid receptor RXR-alpha | polymer | 244 | 27269.5 | 4 | UniProt (P19793) Pfam (PF00104) | Homo sapiens (human) | Nuclear receptor subfamily 2 group B member 1, Retinoid X receptor alpha |
| 2 | E, F (A, D) | 5-(2-{(1Z)-2-methyl-1-[4-(propan-2-yl)benzylidene]-1H-inden-3-yl}ethyl)-1H-tetrazole | non-polymer | 356.5 | 2 | Chemie (K08) | |||
| 3 | G, H, I, J (A, B, C, D) | water | water | 18.0 | 641 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 223 - 462 (UniProt: P19793)
| PDB | External Database | Details |
|---|---|---|
| Gly 219 | - | expression tag |
| Ser 220 | - | expression tag |
| His 221 | - | expression tag |
| Met 222 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 109078.1 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 712.9 | |
| All* | Total formula weight | 109791.0 |
