4N86
Crystal structure of human transthyretin complexed with glabridin
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Transthyretin | polymer | 159 | 17310.5 | 2 | UniProt (P02766) Pfam (PF00576) | Homo sapiens (human) | ATTR, Prealbumin, TBPA |
| 2 | C, E (A, B) | 4-[(3R)-8,8-dimethyl-3,4-dihydro-2H,8H-pyrano[2,3-f]chromen-3-yl]benzene-1,3-diol | non-polymer | 324.4 | 2 | Chemie (GBJ) | |||
| 3 | D (A) | CALCIUM ION | non-polymer | 40.1 | 1 | Chemie (CA) | |||
| 4 | F, G (A, B) | water | water | 18.0 | 76 | Chemie (HOH) |
Sequence modifications
A, B: -19 - 127 (UniProt: P02766)
| PDB | External Database | Details |
|---|---|---|
| Met -31 | - | expression tag |
| Arg -30 | - | expression tag |
| Gly -29 | - | expression tag |
| Ser -28 | - | expression tag |
| His -27 | - | expression tag |
| His -26 | - | expression tag |
| His -25 | - | expression tag |
| His -24 | - | expression tag |
| His -23 | - | expression tag |
| His -22 | - | expression tag |
| Gly -21 | - | expression tag |
| Ser -20 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 34621.0 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 688.8 | |
| All* | Total formula weight | 35309.9 |
