4N7Y

Crystal structure of 14-3-3zeta in complex with a 8-carbon-linker cyclic peptide derived from ExoS

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B	14-3-3 protein zeta/delta	polymer	235	26720.2	2	UniProt (P63104) Pfam (PF00244) In PDB	Homo sapiens (human)	Protein kinase C inhibitor protein 1, KCIP-1
2	C, D	Exoenzyme S	polymer	11	1185.4	2	UniProt (Q93SQ3) In PDB	Pseudomonas aeruginosa
3		water	water		18.0	45	Chemie (HOH)

Sequence modifications

A, B: 1 - 230 (UniProt: P63104)

PDB	External Database	Details
Gly -4	-	expression tag
Ala -3	-	expression tag
Met -2	-	expression tag
Gly -1	-	expression tag
Ser 0	-	expression tag

C, D: 420 - 430 (UniProt: Q93SQ3)

PDB	External Database	Details
2jn 422	Leu 422	engineered mutation
Mk8 425	Ala 425	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	55811.2
All*	Total formula weight	55811.2

*Water molecules are not included.