4N7Q

Crystal structure of eukaryotic THIC from A. thaliana

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	Phosphomethylpyrimidine synthase, chloroplastic	polymer	582	65546.1	1	UniProt (O82392) Pfam (PF01964) In PDB	Arabidopsis thaliana (mouse-ear cress thale-cress)	Hydroxymethylpyrimidine phosphate synthase, HMP-P synthase, HMP-phosphate synthase, HMPP synthase, Protein PYRIMIDINE REQUIRING, Thiamine biosynthesis protein ThiC, Protein THIAMINE C
2	A	HEXANE-1,6-DIOL	non-polymer		118.2	3	Chemie (HEZ)
3	A	COBALT (II) ION	non-polymer		58.9	1	Chemie (CO)
4		water	water		18.0	695	Chemie (HOH)

Sequence modifications

A: 72 - 644 (UniProt: O82392)

PDB	External Database	Details
Met 71	-	initiating methionine
Leu 645	-	expression tag
Glu 646	-	expression tag
His 647	-	expression tag
His 648	-	expression tag
His 649	-	expression tag
His 650	-	expression tag
His 651	-	expression tag
His 652	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	65546.1
Non-Polymers*	Number of molecules	4
	Total formula weight	413.5
All*	Total formula weight	65959.5

*Water molecules are not included.