4N7Q

Crystal structure of eukaryotic THIC from A. thaliana

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0009228	biological_process	thiamine biosynthetic process
A	0016830	molecular_function	carbon-carbon lyase activity
A	0051536	molecular_function	iron-sulfur cluster binding

Functional Information from PDB Data

site_id	AC1
Number of Residues	4
Details	BINDING SITE FOR RESIDUE HEZ A 701

Chain	Residue
A	GLU306
A	GLU306
A	HOH1350
A	HOH1350

---

site_id	AC2
Number of Residues	6
Details	BINDING SITE FOR RESIDUE HEZ A 702

Chain	Residue
A	HOH1292
A	LYS335
A	ARG336
A	TYR391
A	ASP527
A	HOH1060

---

site_id	AC3
Number of Residues	7
Details	BINDING SITE FOR RESIDUE HEZ A 703

Chain	Residue
A	PHE115
A	ASP128
A	TYR130
A	ARG184
A	HOH826
A	HOH1027
A	HOH1476

---

site_id	AC4
Number of Residues	6
Details	BINDING SITE FOR RESIDUE CO A 704

Chain	Residue
A	HIS426
A	HIS490
A	HOH805
A	HOH806
A	HOH807
A	HOH1491

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	11
Details	Binding site: {"evidences":[{"source":"UniProtKB","id":"Q9A6Q5","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	2
Details	Binding site: {"evidences":[{"source":"PubMed","id":"24161603","evidenceCode":"ECO:0000305"}]}

Chain

Residue

Details

---