4N78
The WAVE Regulatory Complex Links Diverse Receptors to the Actin Cytoskeleton
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Cytoplasmic FMR1-interacting protein 1 | polymer | 1253 | 145363.8 | 1 | UniProt (Q7L576) Pfam (PF07159) Pfam (PF05994) | Homo sapiens (human) | Specifically Rac1-associated protein 1, Sra-1, p140sra-1 |
| 2 | B (B) | Nck-associated protein 1 | polymer | 1128 | 128940.7 | 1 | UniProt (Q9Y2A7) Pfam (PF09735) | Homo sapiens (human) | NAP 1, Membrane-associated protein HEM-2, p125Nap1 |
| 3 | C (D) | Wiskott-Aldrich syndrome protein family member 1 | polymer | 559 | 61729.0 | 1 | UniProt (Q92558) Pfam (PF02205) | Homo sapiens (human) | WASP family protein member 1, Protein WAVE-1, Verprolin homology domain-containing protein 1 |
| 4 | D (E) | Protein BRICK1 | polymer | 75 | 8756.9 | 1 | UniProt (Q8WUW1) | Homo sapiens (human) | BRK1 |
| 5 | E (F) | Abl interactor 2 | polymer | 514 | 55807.0 | 1 | UniProt (J3KNB2) Pfam (PF07815) Pfam (PF00018) UniProt (by SIFTS) (Q9NYB9) | Homo sapiens (human) | |
| 6 | F (P) | WIRS | polymer | 15 | 1687.9 | 1 | |||
| 7 | G, M, N, O (A, B) | CHLORIDE ION | non-polymer | 35.5 | 4 | Chemie (CL) | |||
| 8 | H, I, J, K, L... (A, B, F) | GLYCEROL | non-polymer | 92.1 | 16 | Chemie (GOL) | |||
| 9 | AA, BA, CA, DA, EA (A, B, D, E, F) | water | water | 18.0 | 746 | Chemie (HOH) |
Sequence modifications
F: 1 - 513 (UniProt: J3KNB2)
| PDB | External Database | Details |
|---|---|---|
| Ala 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 6 |
| Total formula weight | 402285.2 | |
| Non-Polymers* | Number of molecules | 20 |
| Total formula weight | 1615.3 | |
| All* | Total formula weight | 403900.6 |
