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4N6X

Crystal Structure of the Chemokine Receptor CXCR2 in Complex with the First PDZ Domain of NHERF1

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1ANa(+)/H(+) exchange regulatory cofactor NHE-RF1/Chemokine Receptor CXCR2 fusion proteinpolymer919860.31UniProt (O14745)
Pfam (PF00595)
In PDB
Homo sapiens (human)NHERF-1, Ezrin-radixin-moesin-binding phosphoprotein 50, EBP50, Regulatory cofactor of Na(+)/H(+) exchanger, Sodium-hydrogen exchanger regulatory factor 1, Solute carrier family 9 isoform A3 regulatory factor 1
2ACHLORIDE IONnon-polymer35.54Chemie (CL)
3waterwater18.0105Chemie (HOH)
Sequence modifications
A: 11 - 94 (UniProt: O14745)
PDBExternal DatabaseDetails
Gly 9-expression tag
Met 10-expression tag
Thr 95-SEE REMARK 999
Ser 96-SEE REMARK 999
Thr 97-SEE REMARK 999
Thr 98-SEE REMARK 999
Leu 99-SEE REMARK 999
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight9860.3
Non-Polymers*Number of molecules4
Total formula weight141.8
All*Total formula weight10002.1
*Water molecules are not included.

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PDB entries from 2024-10-09

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