4N6H

1.8 A Structure of the human delta opioid 7TM receptor (PSI Community Target)

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	Soluble cytochrome b562, Delta-type opioid receptor chimeric protein	polymer	414	45878.1	1	UniProt (P0ABE7) UniProt (P41143) Pfam (PF07361) Pfam (PF00001)	Escherichia coli (human)	D-OR-1, DOR-1
2	B, C, D, E, F... (A)	OLEIC ACID	non-polymer		282.5	12	Chemie (OLA)
3	H, I, M, W, X (A)	(2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate	non-polymer		356.5	5	Chemie (OLC)
4	N, O, V (A)	TRIETHYLENE GLYCOL	non-polymer		150.2	3	Chemie (PGE)
5	S (A)	L(+)-TARTARIC ACID	non-polymer		150.1	1	Chemie (TLA)
6	T (A)	(4bS,8R,8aS,14bR)-7-(cyclopropylmethyl)-5,6,7,8,14,14b-hexahydro-4,8-methano[1]benzofuro[2,3-a]pyrido[4,3-b]carbazole-1,8a(9H)-diol	non-polymer		414.5	1	Chemie (EJ4)
7	U (A)	SODIUM ION	non-polymer		23.0	1	Chemie (NA)
8	Y (A)	water	water		18.0	101	Chemie (HOH)

Sequence modifications

A: 1001 - 1106 (UniProt: P0ABE7)

PDB	External Database	Details
Gly 996	-	expression tag
Gly 997	-	expression tag
Thr 998	-	expression tag
Thr 999	-	expression tag
Met 1000	-	expression tag
Trp 1007	Met 29	engineered mutation
Ile 1102	His 124	engineered mutation
Leu 1106	Arg 128	engineered mutation

A: 36 - 338 (UniProt: P41143)

PDB	External Database	Details
Ser 37	Pro 37	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	45878.1
Non-Polymers*	Number of molecules	23
	Total formula weight	6210.3
All*	Total formula weight	52088.4

*Water molecules are not included.